I worked at Alnylam full-time (More than 8 years)
really great science, a lot of good people working there and despite some typical for the industry stumbles they have built quite an impressive track record. Some of the micro-cultures are really great
the place is pretty vertically organized for a company of that size, like all public companies there is a high degree of confidentiality around some issues and some of the micro-cultures are really cut throat
Advice to Management
The bell curve for merit increases can do more harm that good a hyper competitive environment is not helpful or innovation or morale.
Rigorous but great experience. They know exactly what they are looking fur in the candidate. Everyone was candid and curious to know what your strengths are and what you would bring to the table.