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Sage Therapeutics Overview

Cambridge, MA
201 to 500 employees
Company - Public (SAGE)
Biotech & Pharmaceuticals
Unknown / Non-Applicable
Sage Therapeutics is a clinical-stage biopharmaceutical company committed to developing novel medicines to transform the lives of patients with life-altering central nervous system (CNS) disorders.

Sage is thinking differently about drug development by using ... Read more

Mission: At Sage, our mission is to make life better for patients with CNS diseases by discovering, developing, and delivering important new medicines for patients in need.

We’ve worked hard to create an energetic, engaging culture where ideas, creativity ... Read more

Company Updates

  • This week we are thrilled to welcome our 27 Regional Business Directors. Our sales leadership team is now complete and the journey continues as we build-out our inaugural field sales force. If you’re an accomplished health systems/key account manager or specialty sales representative looking to make a meaningful difference in patients’ lives, come unleash your potential with us. #SalesTeam #CommercialHiring #CNS #DoBig #ThisIsSage

  • Each month Sage celebrates employees who embody our Core Values. In July, we found some very BIG gold balloons to help us recognize two individuals and a team for their incredible determination and hard work with the #DoBig Core Value Award #ThisIsSage #EnjoyTheJourney #CoreValues

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Sage Therapeutics – Why Work For Us?

Having fun at the 2017 summer outing in Boston.

 We’ve worked hard to create an energetic, engaging culture where ideas, creativity, and speed are valued. Our people are motivated to work hard, have fun, and deliver on their promises. Each day we are excited by and proud of the work that we do to develop new medicines to treat CNS disorders.  

Winter Celebration 2018 | State Room Boston

 Sage Core Values

Put People First

  • Believe our mission will make a difference in the lives of patients.
  • Keep our patients and their families’ best interest in mind.
  • We value our people and our teams.
  • Care about each other, what we do, and our community.

Be Accountable

  • Be responsible to ourselves, our teams, our company, and our stakeholders.
  • Results and relationships matter.
  • Possess a solution-oriented mindset and execute with a sense of urgency.
  • Make wise decisions in the face of ambiguity.
  • Communicate respectfully and openly.

Do Big

  • Create new opportunities and challenge the conventional wisdom.
  • Think beyond boundaries.
  • Be fearless in our pursuits.
  • Take smart risks always in the best interest of our patients.
  • Collaborate and foster innovation.

Grow Through Learning & Change

  • Understand our industry, strategy, market, and stakeholders.
  • Learn from our successes and challenges.
  • Motivate and empower each other to reach our full potential.
  • Anticipate and embrace change.

Work Fun

  • Celebrate.
  • Be passionate about what we do.
  • Embed excitement and positive energy in our everyday work.
We are a team fearless in our pursuit to discover and develop life-changing therapies

We are a team fearless in our pursuit to discover and develop life-changing therapies for patients living with central nervous system (CNS) disorders. We are passionate about what we do, and when it comes to a great work environment, we deliver - excellent benefits, a rewarding career, and a fun place to work.  

We are a team fearless in our pursuit to discover and develop life-changing therapies.
Sage Therapeutics Science

The human brain is a complex and integrated network. Navigating this intricate circuitry presents a challenge to developing innovative treatments needed for brain disorders. We seek to develop meaningfully differentiated medicines by rethinking disorders of the central nervous system (CNS).

We take a focused, practical and deliberate approach to drug development in pursuit of novel and differentiated medicines for people with CNS disorders. We’re studying the potential of our novel drug candidates to modulate brain activity. Our goal is to develop products that may address gaps in available treatment options. We use a translational research strategy to explore the action of our compounds, and their therapeutic potential for restoring normal CNS function. 


The human brain is a network of billions of nerve cells, connected in complex electrical circuits to communicate. Brain function and mental health depend on these circuits. Neural regulatory pathways, like GABA and NMDA receptors systems, manage the flow of information. Dysfunction in the GABA and NMDA receptor signaling pathways are implicated in a broad range of CNS disorders.

GABA is an inhibitory neurotransmitter found throughout the brain. It binds to its receptors to put the brakes on nerve activity and calm the brain. When out of balance, this pathway potentially plays a role in various CNS disorders, including several neurological and mood disorders.

Activated NMDA receptors increase signaling between nerve cells, and play a critical role in stabilizing neural networks. This excitatory receptor system is also implicated in many psychiatric and neurological CNS disorders. We are helping to pioneer research to understand the role of NMDA receptors in disease.

Sage has designed a large library of novel, proprietary compounds that can specifically modulate GABA or NMDA receptor activity. We’re studying our development compounds for their therapeutic potential in restoring normal CNS function. Our goal is to develop products that may address gaps in available treatment options for CNS disorders. 

Sage Therapeutics Pipeline

Sage Therapeutics Reviews

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Sage Therapeutics CEO Jeff Jonas
Jeff Jonas
31 Ratings
  • Featured Review

    Helpful (5)

    "Sage is the place to be!"

    • Work/Life Balance
    • Culture & Values
    • Career Opportunities
    • Comp & Benefits
    • Senior Management
    Current Employee - Anonymous Employee in Denver, CO
    Current Employee - Anonymous Employee in Denver, CO
    Positive Outlook
    Approves of CEO

    I have been working at Sage Therapeutics full-time (Less than a year)


    When you look at the Sage website you clearly see the values , culture and mission everywhere. When you walk in the doors of Sage, you feel it and see it in everything they do. They expect feedback, they want you to be heard and open to trying new innovative ideas that other companies are too risk averse to try.

    They are building and growing quickly and fitting in the CULTURE is paramount to finding the right people for the roles. At Sage, you have to be able to fit in to that culture of wanting to be an entrepreneur, roll up your sleeves and work hard, but have fun doing it - Work Fun!

    I have never been in a company where you can feel the excitement of everyone that is working there. They are happy, thriving and growing in a place where you are encouraged to think outside the box and push back at every level. It is a breadth of fresh air that I'm excited to see continue for many years to come. They truly put people first! Including Sageans, patients and their families.


    Rapid Growth - it's hard to keep up with the movement and shift of people learning their new roles, but it's also a positive from my perspective.

    Advice to Management

    Keep the culture alive - stay true to the mission and development is the key to ensuring people feel valued and are growing within an organization.

See All 39 Reviews

Sage Therapeutics Photos

Sage Therapeutics photo of: Celebrating Positive Phase 3 data for SAGE-547 in Severe Postpartum Depression
Sage Therapeutics photo of: Science Day at Sage
Sage Therapeutics photo of: Making Elephant Toothpaste
Sage Therapeutics photo of: Team Golf Outing
Sage Therapeutics photo of: 400th Employee
Sage Therapeutics photo of: 300th Employee
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Sage Therapeutics Interviews



Getting an Interview

Getting an Interview




  1. Featured Interview

    Helpful (16)  

    Associate Director Interview

    Anonymous Employee
    Accepted Offer
    Positive Experience
    Average Interview


    The process took 2 weeks. I interviewed at Sage Therapeutics.


    The process was fast and the people were great. My flight home was cancelled due to weather and SAGE had accommodations ready for me before I had time to process being in Boston 2 extra days. Including toiletries and a bottle of red wine to ride out the nor’easter. This is a company that leaves you feeling valued. It is the kind of place you want to work for.

    Interview Questions

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