Mission: At Sage, our mission is to make life better for patients with CNS diseases by discovering, developing, and delivering important new medicines for patients in need.
We’ve worked hard to create an energetic, engaging culture where ideas, creativity ...
At their 90-day mark, we ask employees what they wish they knew before joining.
#SageAdvice #Foodies #PotPie #ThisIsSage
At Sage, Our Employees are the Stars, so it’s not surprising that a spontaneous paparazzi moment happened when we presented the winners of our Core Value Award at the most recent Town Hall meeting. #EmployeesAreTheStars #ThisIsSage #Paparazzi
We’ve worked hard to create an energetic, engaging culture where ideas, creativity, and speed are valued. Our people are motivated to work hard, have fun, and deliver on their promises. Each day we are excited by and proud of the work that we do to develop new medicines to treat CNS disorders.
Put People First
Grow Through Learning & Change
We are a team fearless in our pursuit to discover and develop life-changing therapies for patients living with central nervous system (CNS) disorders. We are passionate about what we do, and when it comes to a great work environment, we deliver - excellent benefits, a rewarding career, and a fun place to work.
The human brain is a complex and integrated network. Navigating this intricate circuitry presents a challenge to developing innovative treatments needed for brain disorders. We seek to develop meaningfully differentiated medicines by rethinking disorders of the central nervous system (CNS).
We take a focused, practical and deliberate approach to drug development in pursuit of novel and differentiated medicines for people with CNS disorders. We’re studying the potential of our novel drug candidates to modulate brain activity. Our goal is to develop products that may address gaps in available treatment options. We use a translational research strategy to explore the action of our compounds, and their therapeutic potential for restoring normal CNS function.
GABA AND NMDA RECEPTORS
The human brain is a network of billions of nerve cells, connected in complex electrical circuits to communicate. Brain function and mental health depend on these circuits. Neural regulatory pathways, like GABA and NMDA receptors systems, manage the flow of information. Dysfunction in the GABA and NMDA receptor signaling pathways are implicated in a broad range of CNS disorders.
GABA is an inhibitory neurotransmitter found throughout the brain. It binds to its receptors to put the brakes on nerve activity and calm the brain. When out of balance, this pathway potentially plays a role in various CNS disorders, including several neurological and mood disorders.
Activated NMDA receptors increase signaling between nerve cells, and play a critical role in stabilizing neural networks. This excitatory receptor system is also implicated in many psychiatric and neurological CNS disorders. We are helping to pioneer research to understand the role of NMDA receptors in disease.
Sage has designed a large library of novel, proprietary compounds that can specifically modulate GABA or NMDA receptor activity. We’re studying our development compounds for their therapeutic potential in restoring normal CNS function. Our goal is to develop products that may address gaps in available treatment options for CNS disorders.
I have been working at Sage Therapeutics full-time
They really care about the people and the science. Take it to a whole new level. There's a real focus on family and employee health that is evident in everything from benefits package to healthy food at lunch and encouraging fitness (running club, support for joining local gym...).
Well, Boston is cold and expensive but it's worth it! Obviously not a Sage thing.
The process took 2 weeks. I interviewed at Sage Therapeutics.
The process was fast and the people were great. My flight home was cancelled due to weather and SAGE had accommodations ready for me before I had time to process being in Boston 2 extra days. Including toiletries and a bottle of red wine to ride out the nor’easter. This is a company that leaves you feeling valued. It is the kind of place you want to work for.
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