Working at Sage Therapeutics | Glassdoor

Sage Therapeutics Overview

Cambridge, MA
201 to 500 employees
Company - Public (SAGE)
Biotech & Pharmaceuticals
Unknown / Non-Applicable
Sage Therapeutics is a clinical-stage biopharmaceutical company committed to developing novel medicines to transform the lives of patients with life-altering central nervous system (CNS) disorders.

Sage is thinking differently about drug development by using ... Read more

Mission: At Sage, our mission is to make life better for patients with CNS diseases by discovering, developing, and delivering important new medicines for patients in need.

We’ve worked hard to create an energetic, engaging culture where ideas, creativity ... Read more

Company Updates

  • At their 90-day mark, we ask employees what they wish they knew before joining.
    #SageAdvice #Foodies #PotPie #ThisIsSage

  • At Sage, Our Employees are the Stars, so it’s not surprising that a spontaneous paparazzi moment happened when we presented the winners of our Core Value Award at the most recent Town Hall meeting. #EmployeesAreTheStars #ThisIsSage #Paparazzi

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Sage Therapeutics – Why Work For Us?

Having fun at the 2017 summer outing in Boston.

 We’ve worked hard to create an energetic, engaging culture where ideas, creativity, and speed are valued. Our people are motivated to work hard, have fun, and deliver on their promises. Each day we are excited by and proud of the work that we do to develop new medicines to treat CNS disorders.  

Winter Celebration 2018 | State Room Boston

 Sage Core Values

Put People First

  • Believe our mission will make a difference in the lives of patients.
  • Keep our patients and their families’ best interest in mind.
  • We value our people and our teams.
  • Care about each other, what we do, and our community.

Be Accountable

  • Be responsible to ourselves, our teams, our company, and our stakeholders.
  • Results and relationships matter.
  • Possess a solution-oriented mindset and execute with a sense of urgency.
  • Make wise decisions in the face of ambiguity.
  • Communicate respectfully and openly.

Do Big

  • Create new opportunities and challenge the conventional wisdom.
  • Think beyond boundaries.
  • Be fearless in our pursuits.
  • Take smart risks always in the best interest of our patients.
  • Collaborate and foster innovation.

Grow Through Learning & Change

  • Understand our industry, strategy, market, and stakeholders.
  • Learn from our successes and challenges.
  • Motivate and empower each other to reach our full potential.
  • Anticipate and embrace change.

Work Fun

  • Celebrate.
  • Be passionate about what we do.
  • Embed excitement and positive energy in our everyday work.
We are a team fearless in our pursuit to discover and develop life-changing therapies

We are a team fearless in our pursuit to discover and develop life-changing therapies for patients living with central nervous system (CNS) disorders. We are passionate about what we do, and when it comes to a great work environment, we deliver - excellent benefits, a rewarding career, and a fun place to work.  

We are a team fearless in our pursuit to discover and develop life-changing therapies.
Sage Therapeutics Science

The human brain is a complex and integrated network. Navigating this intricate circuitry presents a challenge to developing innovative treatments needed for brain disorders. We seek to develop meaningfully differentiated medicines by rethinking disorders of the central nervous system (CNS).

We take a focused, practical and deliberate approach to drug development in pursuit of novel and differentiated medicines for people with CNS disorders. We’re studying the potential of our novel drug candidates to modulate brain activity. Our goal is to develop products that may address gaps in available treatment options. We use a translational research strategy to explore the action of our compounds, and their therapeutic potential for restoring normal CNS function. 


The human brain is a network of billions of nerve cells, connected in complex electrical circuits to communicate. Brain function and mental health depend on these circuits. Neural regulatory pathways, like GABA and NMDA receptors systems, manage the flow of information. Dysfunction in the GABA and NMDA receptor signaling pathways are implicated in a broad range of CNS disorders.

GABA is an inhibitory neurotransmitter found throughout the brain. It binds to its receptors to put the brakes on nerve activity and calm the brain. When out of balance, this pathway potentially plays a role in various CNS disorders, including several neurological and mood disorders.

Activated NMDA receptors increase signaling between nerve cells, and play a critical role in stabilizing neural networks. This excitatory receptor system is also implicated in many psychiatric and neurological CNS disorders. We are helping to pioneer research to understand the role of NMDA receptors in disease.

Sage has designed a large library of novel, proprietary compounds that can specifically modulate GABA or NMDA receptor activity. We’re studying our development compounds for their therapeutic potential in restoring normal CNS function. Our goal is to develop products that may address gaps in available treatment options for CNS disorders. 

Sage Therapeutics Pipeline

Sage Therapeutics Reviews

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Sage Therapeutics CEO Jeff Jonas
Jeff Jonas
25 Ratings
  • Featured Review

    Helpful (1)

    "THE company to be at in Kendall Square"

    • Work/Life Balance
    • Culture & Values
    • Career Opportunities
    • Comp & Benefits
    • Senior Management
    Current Employee - Anonymous Employee
    Current Employee - Anonymous Employee
    Positive Outlook
    Approves of CEO

    I have been working at Sage Therapeutics full-time


    They really care about the people and the science. Take it to a whole new level. There's a real focus on family and employee health that is evident in everything from benefits package to healthy food at lunch and encouraging fitness (running club, support for joining local gym...).


    Well, Boston is cold and expensive but it's worth it! Obviously not a Sage thing.

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Sage Therapeutics Photos

Sage Therapeutics photo of: Celebrating Positive Phase 3 data for SAGE-547 in Severe Postpartum Depression
Sage Therapeutics photo of: Commit to Get Fit Winners
Sage Therapeutics photo of: BlueDot with Sage
Sage Therapeutics photo of: Annual Holiday Lunch & Yankee Swap
Sage Therapeutics photo of: Halloween Costume Contest
Sage Therapeutics photo of: Cambridge Summer Classic 5k Road Race
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Sage Therapeutics Interviews



Getting an Interview

Getting an Interview




  1. Featured Interview

    Helpful (5)  

    Associate Director Interview

    Anonymous Employee
    Accepted Offer
    Positive Experience
    Average Interview


    The process took 2 weeks. I interviewed at Sage Therapeutics.


    The process was fast and the people were great. My flight home was cancelled due to weather and SAGE had accommodations ready for me before I had time to process being in Boston 2 extra days. Including toiletries and a bottle of red wine to ride out the nor’easter. This is a company that leaves you feeling valued. It is the kind of place you want to work for.

    Interview Questions

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Sage Therapeutics Awards & Accolades

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