Working at Sage Therapeutics | Glassdoor
Best Small and Medium Companies to Work For 2020

Sage Therapeutics Overview

Cambridge, MA
501 to 1000 employees
Company - Public (SAGE)
Biotech & Pharmaceuticals
Unknown / Non-Applicable
Sage Therapeutics is a biopharmaceutical company committed to developing novel therapies with the potential to transform the lives of people with debilitating disorders of the brain. We are pursuing new pathways with the goal of improving brain health and our depression ... Read more

Mission: Our mission is to make medicines that matter so people can get better, sooner.

Glassdoor Awards

Best Places to Work: 2020 (#19)

Top CEOs: 2019 (#22)

Company Updates

  • Recently, Sage celebrated National Superhero Day. We’d like to take a moment to thank our very own superheroes on our Facilities team here at Sage! #PutPeopleFirst #ThisIsSage

  • Say hello to our team, fresh out of training and ready to bring exceptional support to PPD patients and their families! #ThisIsSage #RTP #PutPeopleFirst

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Sage Therapeutics Video

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Sage Therapeutics – Why Work With Us?

Having fun at the 2017 summer outing in Boston.

 We’ve worked hard to create an energetic, engaging culture where ideas, creativity, and speed are valued. Our people are motivated to work hard, have fun, and deliver on their promises. Each day we are excited by and proud of the work that we do to develop new medicines to treat CNS disorders.  

Winter Celebration 2018 | State Room Boston

 Sage Core Values

Put People First

  • Believe our mission will make a difference in the lives of patients.
  • Keep our patients and their families’ best interest in mind.
  • We value our people and our teams.
  • Care about each other, what we do, and our community.

Be Accountable

  • Be responsible to ourselves, our teams, our company, and our stakeholders.
  • Results and relationships matter.
  • Possess a solution-oriented mindset and execute with a sense of urgency.
  • Make wise decisions in the face of ambiguity.
  • Communicate respectfully and openly.

Do Big

  • Create new opportunities and challenge the conventional wisdom.
  • Think beyond boundaries.
  • Be fearless in our pursuits.
  • Take smart risks always in the best interest of our patients.
  • Collaborate and foster innovation.

Grow Through Learning & Change

  • Understand our industry, strategy, market, and stakeholders.
  • Learn from our successes and challenges.
  • Motivate and empower each other to reach our full potential.
  • Anticipate and embrace change.

Work Fun

  • Celebrate.
  • Be passionate about what we do.
  • Embed excitement and positive energy in our everyday work.
We are a team fearless in our pursuit to discover and develop life-changing therapies

We are a team fearless in our pursuit to discover and develop life-changing therapies for patients living with central nervous system (CNS) disorders. We are passionate about what we do, and when it comes to a great work environment, we deliver - excellent benefits, a rewarding career, and a fun place to work.  

We are a team fearless in our pursuit to discover and develop life-changing therapies.
Sage Therapeutics Science

The human brain is a complex and integrated network. Navigating this intricate circuitry presents a challenge to developing innovative treatments needed for brain disorders. We seek to develop meaningfully differentiated medicines by rethinking disorders of the central nervous system (CNS).

We take a focused, practical and deliberate approach to drug development in pursuit of novel and differentiated medicines for people with CNS disorders. We’re studying the potential of our novel drug candidates to modulate brain activity. Our goal is to develop products that may address gaps in available treatment options. We use a translational research strategy to explore the action of our compounds, and their therapeutic potential for restoring normal CNS function. 


The human brain is a network of billions of nerve cells, connected in complex electrical circuits to communicate. Brain function and mental health depend on these circuits. Neural regulatory pathways, like GABA and NMDA receptors systems, manage the flow of information. Dysfunction in the GABA and NMDA receptor signaling pathways are implicated in a broad range of CNS disorders.

GABA is an inhibitory neurotransmitter found throughout the brain. It binds to its receptors to put the brakes on nerve activity and calm the brain. When out of balance, this pathway potentially plays a role in various CNS disorders, including several neurological and mood disorders.

Activated NMDA receptors increase signaling between nerve cells, and play a critical role in stabilizing neural networks. This excitatory receptor system is also implicated in many psychiatric and neurological CNS disorders. We are helping to pioneer research to understand the role of NMDA receptors in disease.

Sage has designed a large library of novel, proprietary compounds that can specifically modulate GABA or NMDA receptor activity. We’re studying our development compounds for their therapeutic potential in restoring normal CNS function. Our goal is to develop products that may address gaps in available treatment options for CNS disorders. 

Sage Therapeutics Pipeline

Sage Therapeutics Reviews

  • Featured Review

    Helpful (1)

    "Refreshingly innovative workplace!"

    • Work/Life Balance
    • Culture & Values
    • Career Opportunities
    • Comp & Benefits
    • Senior Management
    Current Employee - Manager in Cambridge, MA
    Current Employee - Manager in Cambridge, MA
    Positive Outlook
    Approves of CEO

    I have been working at Sage Therapeutics full-time (More than a year)


    - Rooted in science.
    - Tremendously mission focused.
    - High emphasis on innovation and originality.
    - Growth mindset and surrounded by high performers.
    - Deliberately authentic work culture.
    - Very competitive benefits.
    - Fabulous HR department - very thoughtful, creative engagement plan.


    - As a rapidly evolving company, it maybe challenging for folks who value steady state stability in daily activities

    Advice to Management

    Please continue prioritizing the preservation and nourishment of our culture. We are enormously grateful for this!!

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Sage Therapeutics Photos

Sage Therapeutics photo of: Today we want to take a moment to thank the wonderful women of our leadership team here at Sage! The support you provide all Sageans is truly invaluable! #InternationalWomensDay #WomenInLeadership
Sage Therapeutics photo of: Sage celebrates Diwali the festival of lights!
Sage Therapeutics photo of: Career Development Week 2019
Sage Therapeutics photo of: Sage Gives Back at 2019 Cradles to Crayons
Sage Therapeutics photo of: Every other Friday during the summer, Sageans who work hard all week take a half day to get a head start on their weekend.
Sage Therapeutics photo of: Fulfillment of Purposeful Work
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Sage Therapeutics Interviews



Getting an Interview

Getting an Interview




  1. Helpful (20)  

    Associate Director Interview

    Anonymous Employee
    Accepted Offer
    Positive Experience
    Average Interview


    The process took 2 weeks. I interviewed at Sage Therapeutics.


    The process was fast and the people were great. My flight home was cancelled due to weather and SAGE had accommodations ready for me before I had time to process being in Boston 2 extra days. Including toiletries and a bottle of red wine to ride out the nor’easter. This is a company that leaves you feeling valued. It is the kind of place you want to work for.

    Interview Questions

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Sage Therapeutics Awards & Accolades

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