Pros
Interesting science at scale, free bus from Cambridge and train station, salaries are better than University, but can easily be beaten by surrounding companies & institutes (EBI). Depending on department, can be fairly relaxed.
Cons
They tell you, you are at Sanger for the science, everything else like salaries, acknowledgment, career progression, go somewhere else. They are trying to change their ways (technician commitment is a UK wide campaign that just started at Sanger and doesn't have any real value for existing employees, maybe now improved?). Salaries are capped, meaning there is only X amount to give out, if everyone performs exceptionally well, unfortunately not everyone will be rewarded at the same level. Career progression doesn't exist, but most academic organizations follow the same system. Recently, Sanger has been hit by scandals, from bullying to misuse of african data all reported by the media. Everyone has an opinion whether its true or not, but even having a hint of this type of toxic environment in the public realm is not a good look.